Remimazolam TIVA-Flumazenil Anesthesia in Short ENT Surgeries

Tongji Hospital

Status: Not yet enrolling

Conditions: Remimazolam; Total Intravenous Anesthesia; Bispectral Index

Study type: Observational

Funder types: Other

Identifiers

NCT07389798

RTFA

Details and patient eligibility

About

This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism based on whether their intraoperative BIS values were maintained below 60.

Full description

This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism into two groups based on whether their intraoperative BIS values were maintained below 60. It aims to compare the differences in postoperative recovery quality between the groups, thereby providing evidence-based support for determining the optimal BIS target range during remimazolam TIVA.

Enrollment: 600 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-65 years
• ASA I-III
• Underwent short-duration ENT surgery
• Underwent remimazolam TIVA combined with flumazenil antagonism.
• Continuous intraoperative BIS monitoring

Exclusion criteria

• Comorbid severe underlying diseases
• Intraoperative BIS data were missing or incompletely recorded
• Severe lack of medical records

Trial design

600 participants in 2 patient groups

AB group

Description:

Intraoperative BIS values ≤60

HB group

Description:

Intraoperative BIS values \>60