Remineralization of Caries Affected Dentin

Al-Azhar University

Status: Completed

Conditions: Deep Caries

Treatments: Other: Pulpine with Polyamidoamine Dendrimer

Study type: Interventional

Funder types: Other

Identifiers

NCT04262076

REC17-01123

Details and patient eligibility

About

Remineralization of carious affected dentin

Full description

Remineralization of Carious affected dentin by using Pulpine alone and combination of Pulpine with Polyamidoamine Dendrimer.

Enrollment: 14 patients

Sex: All

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Presence of at least one class one carious posterior teeth in both left and right side.
• Absence of spontaneous pain, Mobility and tenderness on percussion.
• Radiographically, the preoperative inclusion criteria are, no internal or external resorption and no widening of the periodontal membrane space.

Exclusion criteria

• Patients with poor oral Hygiene.
• Evidence of Rampant Caries.
• Teeth with periodontal involvement.
• Poor general health condition.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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14 participants in 2 patient groups

Combination of pulpine with Polyamidoamine Dendrimer

Experimental group

Description:

Removal of Caries infected dentin from the walls and floor of the cavity and then apply polyamidoamine Denrimer for 30 secs ,then washed out of the cavity followed by placement of Pulpine over affected Dentin.

Treatment:

Other: Pulpine with Polyamidoamine Dendrimer

Pulpine

Active Comparator group

Description:

Removal of Caries infected dentin from the walls and the floor of the cavity followed by application of Pulpine over affected Dentin.

Treatment:

Other: Pulpine with Polyamidoamine Dendrimer