Remission in Adults With Severe Asthma in Thailand

Thammasat University

Status: Not yet enrolling

Conditions: Severe Asthma; Asthma Control Level

Treatments: Diagnostic Test: Fractional exhaled nitric oxide (FeNO) test; Diagnostic Test: Blood eosinophil count (BEC); Other: Global Initiative for Asthma (GINA) and Asthma Control Test (ACT) questionnaires; Diagnostic Test: Spirometry

Study type: Observational

Funder types: Other

Identifiers

NCT07328035

MTU-EC-IM-0-283/68

Details and patient eligibility

About

The goal of this observational study is to determine the prevalence of remission among adults with severe asthma, as well as the factors associated with remission in Thailand.

The main question the study aims to answer is:

What is the prevalence of remission among adults with severe asthma in Thailand? Participants will complete questionnaires on asthma symptoms and undergo pulmonary function testing and a blood test once.

Full description

This study is a cross-sectional study. Thai patients aged 18 years or older with severe asthma are included in the study. Participants will complete two questionnaires about asthma control: the Global Initiative for Asthma (GINA) and the Asthma Control Test (ACT), and will perform spirometry, a fractional exhaled nitric oxide (FeNO) test, and blood eosinophil counts (BEC).

Enrollment: 230 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• severe asthma
• age 18 years or older

Exclusion criteria

• inability to perform spirometry or fractional exhaled nitric oxide (FeNO) test

Trial design

230 participants in 1 patient group

Severe asthma

Description:

Asthma that requires treatment with high-dose inhaled corticosteroids plus a second controller, or requires systemic corticosteroids for ≥50% of the previous year to prevent it from becoming uncontrolled, or remains uncontrolled despite this therapy.

Treatment:

Diagnostic Test: Spirometry

Other: Global Initiative for Asthma (GINA) and Asthma Control Test (ACT) questionnaires

Diagnostic Test: Blood eosinophil count (BEC)

Diagnostic Test: Fractional exhaled nitric oxide (FeNO) test