Remote Ischemic Preconditioning in Cardiac Surgery

Assiut University

Status: Unknown

Conditions: Ischemia Reperfusion Injury

Treatments: Procedure: Sham remote ischemic preconditioning; Procedure: remote ischemic preconditioning

Study type: Interventional

Funder types: Other

Identifiers

NCT04647370

Ischemic Preconditioning

Details and patient eligibility

About

Aim of the work :

Evaluation of the role of Remote Ischemic Preconditioning (RIP) on liver function in patients undergoing on-pump cardiac surgery.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Being candidate for on-pump cardiac surgery.
2. Willing to participate in the study
3. Ages eligible for the study: 18 to 70 years.
4. Gender eligible for the study : both

Exclusion criteria

1. Patient refusal.
2. Known cause of possible liver function disturbances that includes right heart failure, acute inflammation of gallbladder or any other complication of gallstone disease.
3. Active viral and non viral hepatitis.
4. Pregnant women.
5. History of peripheral nerve disease or peripheral vascular disease of the extremities

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 2 patient groups

Remote ischemic preconditioning

Active Comparator group

Treatment:

Procedure: remote ischemic preconditioning

Sham remote ischemic preconditioning

Sham Comparator group

Treatment:

Procedure: Sham remote ischemic preconditioning