Remotely Supervised Exercise for Adults With Cystic Fibrosis

European University

Status: Completed

Conditions: Cystic Fibrosis

Treatments: Other: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05173194

FQKloE-II

Details and patient eligibility

About

Cystic fibrosis (CF) is a genetic disease characterized by abnormal chloride transport in epithelial tissues. Inflammation is a key component contributing to the main alterations induced by the disease. The increase in life expectancy comes with a higher prevalence of CF-related comorbidities, but also with new emerging complications directly related to aging. Physical fitness and exercise practice have been previously associated to survival and better quality of life in patients with cystic fibrosis. Thus, the aim of this study is to assess the effects of a remotely supervised resistance exercise program on lung function, muscle strength, body composition, quality of life and inflammatory markers in adult patients with cystic fibrosis.

Full description

This study aims to assess the effects of a remotely supervised resistance exercise program on lung function, muscle strength, body composition, quality of life and inflammatory markers in adult patients with cystic fibrosis.

Enrollment: 32 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed clinical and genetic diagnosis for cystic fibrosis;
• Age from 16 years.

Exclusion criteria

• Musculoskeletal disorders that do not allow the performance of physical exercise;
• Pregnancy;
• Absence of registration of clinical required.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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32 participants in 2 patient groups

Telematic Exercise

Experimental group

Description:

A remotely supervised resistance exercise program will be carried out for 8 weeks, with three weekly sessions lasting approximately 60 minutes each. Training will be performed in groups of four patients, according to their lung function/physical fitness. The first training session will be on site (University) for familiarization, planning and adjustment of the exercises, and the following sessions will be performed online. Each session is divided into: (i) Warm-up and joint mobility; (ii) main part: strength exercises for different muscle groups; and (iii) cool down: stretching and breathing exercises.

Treatment:

Other: Exercise

Control

No Intervention group

Description:

Control group will follow routine recommendations from the multidisciplinary CF team.