Removal of Erroneous Penicillin Allergy Labels: Implementation Study (REPeAL)

Royal Cornwall Hospitals Trust

Status

Active, not recruiting

Conditions

Penicillin Allergy

Study type

Observational

Funder types

Other

Identifiers

NCT06528106

335337 (Other Identifier)

NIHR300542 (Other Grant/Funding Number)

2324.RCHT.66

Details and patient eligibility

About

To test the implementation of penicillin allergy de-labelling delivered by the responsible clinical teams and the antimicrobial stewardship teams across all medical, surgical and critical care specialities in a UK hospital using the developed toolkit and a validated penicillin allergy decision support tool.

Full description

Aim:

To test implementation of the penicillin allergy de-labelling complex intervention in surgical, medical and critical care patient pathway.

Objectives:

To use the Institute for Health Improvement (IHI) Model for Improvement methodology to implement the penicillin allergy de-labelling complex intervention in each setting (surgery, medicine, critical care)
To measure the number of patients meeting inclusion criteria (>16 with a penA not prescribed first line antibiotics) who have had their penicillin allergy record assessed by the wider clinical teams and separately by the AMS team.
To measure the patient uptake of penicillin allergy record removal (i.e. the rate of patient declining de-label / DOC).

To interview 10-15 patients and 10-15 healthcare workers to gain insight into the penicillin allergy de labelling process.

Enrollment

30 estimated patients

Sex

All

Ages

18 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All adult (>16) patients admitted to hospital over the study period with a penicillin allergy record preventing first line antibiotic use.

Exclusion criteria