Removal of Protein Bound Uremic Toxins by Modified Plasma Separation and Adsorption Combined With Hemodialysis

Rigshospitalet

Status: Unknown

Conditions: Uremia

Treatments: Procedure: mFPSA treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT00375635

MBD2006

Details and patient eligibility

About

The aim of this study is to examine removal of protein bound uremic substances by mFPSA in chronic hemodialysis patients. mFPSA is an extracorporal blood purification system developed for detoxification in acute liver failure by removal of protein bound as well as water soluble substances.

Full description

Measurements of uremic protein bound substances before and after mFPSA and a preceding routine hemodialysis session.

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Over the age of 18
• Anuria
• Chronic hemodialysis dependence

Exclusion criteria

• No present history of bleeding episodes
• Cardiac diseases

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)