Removal of Uremic Toxins With Nocturnal Dialysis Versus Standard Dialysis

Ghent University Hospital (UZ)

Status: Completed

Conditions: Chronic Renal Failure

Treatments: Procedure: Standard dialysis; Procedure: Nocturnal dialysis

Study type: Interventional

Funder types: Other

Identifiers

NCT00766792

2005/288

Details and patient eligibility

About

Dialysis patients, who decide to switch from standard dialysis (3 times 240-270 min/week) to nocturnal dialysis (3 times 480 min/week), will be followed. In parallel a control group with patients staying on standard dialysis will be followed. The study will last 30 weeks. During this period blood samples (pre- and post-dialysis: 10 times; inlet and outlet of dialyzer: 3 times) will be collected on predetermined time points. Concentration of several uremic retention solutes will be determined.

Enrollment: 15 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age > 18 years

Exclusion criteria

• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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15 participants in 2 patient groups

1

Experimental group

Description:

Nocturnal dialysis

Treatment:

Procedure: Nocturnal dialysis

2

Active Comparator group

Description:

Standard dialysis

Treatment:

Procedure: Standard dialysis