Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites

Hvidovre University Hospital

Status and phase: Completed; Phase 3; Phase 2

Conditions: Cirrhosis; Ascites

Treatments: Drug: Terlipressin

Study type: Interventional

Funder types: Other

Identifiers

NCT00115947

2004-000568-29

Details and patient eligibility

About

The purpose of this study is to investigate the effect of terlipressin on myocardial perfusion and renal function.

Hypothesis: Significant improvement of renal function reflected by: glomerular filtration rate (GFR), renal blood flow (RBF), excretion of salt and metabolites in the urine and related hormones and peptides in the blood. No effect on the systolic function of the heart.

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Cirrhosis and ascites