Renal Denervation in End Stage Renal Disease Patients With Refractory Hypertension

Medtronic

Status and phase: Completed; Phase 1

Conditions: Renal Dialysis; Kidney Failure, Chronic

Treatments: Device: Renal Denervation with a catheter-based procedure

Study type: Interventional

Funder types: Industry

Identifiers

NCT00753116

TP-041

Details and patient eligibility

About

The purpose of this this study is to investigate the clinical utility of renal denervation in the treatment of ESRD patients with refractory hypertension.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Systolic blood pressure of 160 mmHg or greater
• On 3 or more antihypertensive medications
• On dialysis for more than 6 months

Exclusion criteria

• Renal artery abnormalities
• Known secondary hypertension attributable to a cause other than sleep apnea
• MI, angina, CVA within 6 months
• Others

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)