Renal Fractional Flow Reserve in Renal Artery Stenting (PREFFER)

National Institute of Cardiology, Warsaw, Poland

Status: Completed

Conditions: Hypertension; Renal Artery Stenosis

Treatments: Procedure: Renal artery stenting

Study type: Interventional

Funder types: Other

Identifiers

NCT01128933

2P05B02530

Details and patient eligibility

About

The purpose of the study is to determine potential utility of renal fractional flow reserve in prognosis predicting after renal stent implantation.

Enrollment: 45 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least moderate (60% or more) renal artery stenosis with atheromatic appearance in angiography
• Hypertension defined according to WHO criteria
• Age 18-75 years
• Signed informed consent obtained

Exclusion criteria

• Bilateral renal artery stenosis or significant renal artery stenosis in solitary kidney
• Contraindications to percutaneous renal angioplasty with stenting
• Atrophy of the kidney supplied with stenosed artery
• Other well known secondary reason for hypertension
• Chronic heart failure NYHA II-IV
• Significant valvular heart disease qualified for surgery
• Persistent atrial fibrillation
• Renal failure with GFR below 30ml/min

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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45 participants in 1 patient group

Hypertensive patients

Experimental group

Description:

Hypertensive patients with at least moderate renal artery stenosis

Treatment:

Procedure: Renal artery stenting