Renal Function During Laparoscopic Surgery

Catholic University of the Sacred Heart

Status: Completed

Conditions: Intra Operative Fluid Management

Treatments: Drug: Dopamine

Study type: Interventional

Funder types: Other

Identifiers

NCT01722630

FRF-2012-DH

Details and patient eligibility

About

Aim of this study was to investigate the cardiac and renal responses to the administration of different amount of crystalloids, with and without dopamine, during gynaecological laparoscopic surgery.

Enrollment: 60 patients

Sex: Female

Ages: 24 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I
• age 24-42
• patients undergoing gynaecological laparoscopy

Exclusion criteria

• cardiovascular diseases
• renal and endocrine disorders
• obesity (BMI > 30 Kg/m2)
• the assumption of drugs that could interfere with renal parameters considered in the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

control

No Intervention group

Description:

Patients received intravenously saline solution at 5 ml/Kg/h

dopamine

Experimental group

Description:

Patients received intravenously saline solution at 5 ml/Kg/h and dopamine at 3 mcg/Kg/min

Treatment:

Drug: Dopamine

crystalloids

No Intervention group

Description:

Patients received intravenously saline solution at 10 ml/Kg/h