Acute Kidney Injury and Acute Kidney Disease in COVID-19

University of Giessen

Status: Completed

Conditions: Corona Virus Infection; Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT04353583

AZ 58/20

Details and patient eligibility

About

Acute kidney injury (AKI) has been identified as an independent risk factor for in-hospital mortality. The present study aims to investigate the incidence of AKI and renal recovery of inpatients diagnosed with COVID-19.

Full description

Beginning in December 2019, a novel coronavirus, designated as severe acute respiratory distress coronavirus 2 (SARS-CoV-2), has caused an international outbreak of respiratory illness termed coronavirus disease 2019 (COVID-19). Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, some patients show severe kidney abnormalities. Acute kidney injury (AKI) has been identified as an independent risk factor for in-hospital mortality. The present study aims to investigate the incidence of AKI and renal recovery of inpatients diagnosed with COVID-19.

Enrollment: 900 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with COVID-19 diagnosed by World Health Organisation (WHO) criteria

Exclusion criteria

1. Patients aged less than 18 years
2. Patients with stage 4 chronic kidney disease (baseline estimated glomerular filtration rate <30 ml/min/1.73 m2)
3. Patients receiving maintenance dialysis
4. Recipients of solid-organ transplantation

Trial design

900 participants in 2 patient groups

ICU patients

Description:

Inpatients with COVID-19 requiring ICU care

Non-ICU patients

Description:

Inpatients with COVID-19 not requiring ICU care