Renal Parenchymal Core Needle Biopsy

Modarres Hospital

Status: Completed

Conditions: Kidney Glomerulus; Complications; Image-guided Biopsy

Treatments: Device: noncoaxial renal biopsy; Device: coaxial renal biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT02758535

Renal Parenchymal Biopsy

Details and patient eligibility

About

Percutaneous image-guided parenchymal renal biopsy has been used to detect the different pathologies of renal parenchyma, to define the degree of reversible changes, and to define when the medical treatment fails. Percutaneous core needle renal biopsy has been reported to have a higher diagnostic yield compared to fine needle aspiration. Percutaneous core needle renal biopsy is usually based on tissue sampling under guidance of either sonography or computed tomography. Renal parenchymal biopsy can be done either with a coaxial or noncoaxial technique. In coaxial technique, the introducing needle is placed in the renal parenchyma; then, multiple tissue sampling can be performed throughout the same tract. Alternatively, in noncoaxial technique, biopsy needle is inserted repeatedly for each tissue sampling. Although there are some reports regarding the comparison of coaxial and noncoaxial methods of renal mass biopsy, comparison of the two methods in renal parenchymal biopsy has not yet been described in the literature. In this prospective study, the investigators sought to compare the procedural time and the complication rate of coaxial technique with those of noncoaxial technique in percutaneous renal parenchymal biopsy.

Enrollment: 166 patients

Sex: Male

Ages: 10 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• impaired renal function
• proteinuria
• hematuria

Exclusion criteria

• renal hydronephrosis
• chronic renal failure
• a history of renal cell carcinoma
• suspicious renal mass
• uncorrectable coagulopathy

Trial design

166 participants in 2 patient groups

Core needle biopsy with coaxial method

Experimental group

Description:

The patients undergo renal biopsy with a coaxial Tru-Cut needle

Treatment:

Device: coaxial renal biopsy

Core needle biopsy with noncoaxial method

Experimental group

Description:

The patients undergo renal biopsy with a noncoaxial Tru-Cut needle

Treatment:

Device: noncoaxial renal biopsy