Renal Parenchymal Core Needle Biopsy

M

Modarres Hospital

Status

Completed

Conditions

Kidney Glomerulus
Complications
Image-guided Biopsy

Treatments

Device: noncoaxial renal biopsy
Device: coaxial renal biopsy

Study type

Interventional

Funder types

Other

Identifiers

NCT02758535
Renal Parenchymal Biopsy

Details and patient eligibility

About

Percutaneous image-guided parenchymal renal biopsy has been used to detect the different pathologies of renal parenchyma, to define the degree of reversible changes, and to define when the medical treatment fails. Percutaneous core needle renal biopsy has been reported to have a higher diagnostic yield compared to fine needle aspiration. Percutaneous core needle renal biopsy is usually based on tissue sampling under guidance of either sonography or computed tomography. Renal parenchymal biopsy can be done either with a coaxial or noncoaxial technique. In coaxial technique, the introducing needle is placed in the renal parenchyma; then, multiple tissue sampling can be performed throughout the same tract. Alternatively, in noncoaxial technique, biopsy needle is inserted repeatedly for each tissue sampling. Although there are some reports regarding the comparison of coaxial and noncoaxial methods of renal mass biopsy, comparison of the two methods in renal parenchymal biopsy has not yet been described in the literature. In this prospective study, the investigators sought to compare the procedural time and the complication rate of coaxial technique with those of noncoaxial technique in percutaneous renal parenchymal biopsy.

Enrollment

166 patients

Sex

Male

Ages

10 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • impaired renal function
  • proteinuria
  • hematuria

Exclusion criteria

  • renal hydronephrosis
  • chronic renal failure
  • a history of renal cell carcinoma
  • suspicious renal mass
  • uncorrectable coagulopathy

Trial design

166 participants in 2 patient groups

Core needle biopsy with coaxial method
Experimental group
Description:
The patients undergo renal biopsy with a coaxial Tru-Cut needle
Treatment:
Device: coaxial renal biopsy
Core needle biopsy with noncoaxial method
Experimental group
Description:
The patients undergo renal biopsy with a noncoaxial Tru-Cut needle
Treatment:
Device: noncoaxial renal biopsy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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