Renal Perfusion Assessment in the Endovascular Treatment of Renal Artery Stenosis

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Enrolling

Conditions: Renal Artery Stenosis

Study type: Observational

Funder types: Other

Identifiers

NCT05603221

ASL and PBV in RAS

Details and patient eligibility

About

The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal perfusion after endovascular treatment in renal artery stenosis.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who provided informed consent
• patients who were diagnosed with RAS by CTA, MRA, or Doppler ultrasonography
• patients who were aged 18 years or older
• patients whose intervened renal arteries were not completely occluded (confirmed by DSA)
• the stenosis percentage exceeding 70%
• patients who had uncontrolled blood pressure or impaired renal function
• paitents whose affected kidney did not have total loss of function

Exclusion criteria

• were pregnant
• had a history of renal transplantation or renal artery bypass surgery
• were allergic to iodine contrast medium
• had other contraindications of endovascular treatment
• contraindications of MRI examinations
• had technical failure in the endovascular treatment.

Trial design

30 participants in 1 patient group

Endovascular Group

Description:

Patients who had successful endovascular revascularization