Renal Recovery After PEEP Weaning in ARDS (RE2SDRA)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: ARDS (Acute Respiratory Distress Syndrome); AKI - Acute Kidney Injury

Study type: Observational

Funder types: Other

Identifiers

NCT06754787

29BRC24.0031 - RE2SDRA

Details and patient eligibility

About

The purpose of the study is to investigate renal recovery in ARDS after PEEP weaning. The primary outcome was the variation of the hourly urine output (HUO), 48 h after PEEP weaning. Secondary outcomes were the need for RRT and mortality. Two groups were defined depending wether hourly urine output was greater or lower than 0.35 mL/kg/h.

Enrollment: 120 patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• intubated for more than 48 hours, exposed to a PEEP≥ 8 cmH20

Exclusion criteria

• chronic end-stage renal disease on admission
• refusal to participate
• non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity
• under legal protection.