Renal Tubular Acidosis in Incident Renal Transplant Recipients

Universitaire Ziekenhuizen KU Leuven

Status: Unknown

Conditions: Renal Transplant Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT01283880

ML6919

Details and patient eligibility

About

Metabolic acidosis is a common complication in incident renal transplant recipients. Protracted acidosis may be associated with osteoporosis, inflammation, negative protein balance and malnutrition, and last but not least may cause renal dysfunction. Preliminary data indicate an increased prevalence of nephrocalcinosis in renal transplant biopsies of incident patients presenting with metabolic acidosis. The present study aims (1)evaluate the prevalence and type of renal tubular acidosis (RTA) in incident renal transplant recipients and to identify clinical correlates and (2) to find associations between RTA, nephrolithiasis and nephrocalcinosis

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Recipient of a single kidney transplant included in the protocol biopsy program.
• eGFR > 30 ml/min
• Age ≥ 18 years
• Written informed consent

Exclusion criteria

• none