Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap

The Second Hospital of Tangshan

Status: Completed

Conditions: Disruption of Nerve Repair; Infection Wound

Treatments: Device: Nerve flap

Study type: Interventional

Funder types: Other

Identifiers

NCT01707654

HEBEI-J06451 (Other Identifier)

TSChen6017

Details and patient eligibility

About

A combination of soft tissue and digital nerve defects in the finger results in sensory loss of the finger pulp. Reconstruction of these combined injuries is difficult. When the neurocutaneous defect is associated with wound infection, reconstructive alternatives are more limited. From July 2008 to May 2010, a retrospective study was conducted with 9 consecutive postinfection patients who had the neurocutaneous defect of the finger following trauma. The purpose of this retrospective study is to report repair of the complicated infected wound in the finger using the bipedicled nerve flap and to evaluate the efficacy of this technique.

Full description

sensation of the flaps is assessed using static two-point discrimination (2PD) and Semmes-Weinstein monofilament (SWM) testing at final follow-up. The cold intolerance of the injured finger is measured using the self-administered Cold Intolerance Severity Score questionnaire that was rated into mild, moderate, severe, and extreme (0-25, 26-50, 51-75 and 76-100). Patients report their satisfaction with functional recovery of the injured finger according to the Michigan Hand Outcomes Questionnaire that was based on a 5-point response scale.

Enrollment: 9 patients

Sex: All

Ages: 16 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• an infective wound with exposed bone or tendon in the finger;
• soft tissue defect involving proximal half of the middle phalanx, the proximal phalanx, or both;
• associated digital nerve defect 1 to 4 cm in length;
• single or double nerve defects; and
• simultaneous repair of nerve and soft tissue defects.

Exclusion criteria

• injury to the course of the pedicle or the donor site;
• nerve defect less than 1 cm or larger than 4 cm in length;
• occurrence of the defect in a region the flap is unable to reach, such as distal interphalangeal joint region, distal portion of the middle phalanx of the middle finger and the thumb;
• no involvement of the digital nerve.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 1 patient group

nerve graft

Other group

Description:

Simultaneous repair of the infected wound and digital nerve defect in the finger using a bipedicled nerve flap including nerve graft from the dorsal branch of the digital nerve.

Treatment:

Device: Nerve flap