Repair of the Large Bone Defects Through 3D Printed Individualized Porous Implant

P

Peking University

Status

Unknown

Conditions

Large Bone Defects

Treatments

Device: 3D printed individualized porous implants

Study type

Observational

Funder types

Other

Identifiers

NCT04466397
Liuzhongjun-1

Details and patient eligibility

About

The aim of this study was to investigate the simply use of three-dimensional (3D) printed individualized porous implants in the absence of autogenous/allogeneic bone graft or any osteoinductive agents to treat the large bone defects caused by varies of pathogenesis and systematically study its long-term therapeutic effect and osseointegration characteristics.

Full description

A selection of fifty-eight patients with large bone defects caused by tumor, infection or trauma received the individualized porous implants treatment, and two typical cases were chosen for detailed study. Further, the large segmental femur defect model of sheep was utilized to study the osseointegration characteristics of the individualized porous implants in 1, 3, 6 months after implantation.

Enrollment

60 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Large bone defects (>4cm) in spine, limb bone and hip joint caused by tumor, infection or other pathogenesis received the individualized porous implants treatment.Exclusion Criteria:

  • Bone defects less than 4cm long.
  • Bone defects treated by other methods ,such as ilizarov technique, masquelet technique or Ti mesh.

Trial design

60 participants in 1 patient group

3D printed implants reconstruction group
Description:
The patients with large bone defects who treated by 3D printed individualized porous implants
Treatment:
Device: 3D printed individualized porous implants

Trial contacts and locations

0

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Central trial contact

Teng Zhang, PhD

Data sourced from clinicaltrials.gov

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