Repeated-dose Behavioral Intervention to Reduce Opioid Overdose (REBOOT)

San Francisco Department of Public Health

Status

Completed

Conditions

Opioid-Related Disorders

Drug Overdose

Treatments

Behavioral: REBOOT

Study type

Interventional

Funder types

Other

Identifiers

NCT03838510

5R01DA045690-02

Details and patient eligibility

About

REBOOT is a randomized trial of a repeated-dose brief intervention to reduce overdose and risk behaviors among naloxone recipients with opioid use disorder. It includes an established overdose education curriculum within an Informational-Motivation-Behavior (IMB) model. This study will test the efficacy of REBOOT vs attention-control.

Enrollment

268 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18-65 years
Characteristics of opioid use history
Previously received take-home naloxone
No life-threatening illness likely to progress clinically during trial
Able/willing to provide informed consent and locator information, communicate in English, and adhere to visit schedule

Exclusion criteria

Suicidal ideation
Participating in another interventional study that could possibly impact the study's outcomes of interest
Planning to leave San Francisco/Boston metro area during study
Previously exposed to REBOOT counseling intervention
Any condition that, in the Principal Investigator's judgment, interferes with safe study participation or adherence to study procedures