Repetitive Transcranial Magnetic Stimulation

Heinrich-Heine University, Duesseldorf

Status: Completed

Conditions: Schizophrenia

Treatments: Procedure: rTMS, "repetitive transcranial magnetic stimulation"; Other: rTMS

Study type: Interventional

Funder types: Other

Identifiers

NCT00169689

TMS_01

TMS_S_01

Details and patient eligibility

About

The study is a prospective, randomized, double-blind sham-controlled study.

Full description

The principal objective of this trial is to investigate the effect of left prefrontal high frequency rTMS on negative symptoms in schizophrenia.

Enrollment: 40 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• DSM-IV criteria for schizophrenia
• age between 18 and 60
• informed consent
• right handed patient
• no change of antipsychotic treatment > 2 weeks before recruitment

Exclusion criteria

• seizures, epilepsy
• history of severe head injury
• status post implantation of a cardiac pacemaker or other electronic devi-ses

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 1 patient group

rTMS

Sham Comparator group

Description:

sham coil system versus verum rTMS stimulation

Treatment:

Procedure: rTMS, "repetitive transcranial magnetic stimulation"

Other: rTMS