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Repetitive Transcranial Magnetic Stimulation for Freezing of Gait

D

Dongtan Sacred Heart Hospital

Status

Completed

Conditions

Parkinsonian Disorders

Treatments

Device: rTMS Supplementary motor area
Device: rTMS Motor cortex

Study type

Interventional

Funder types

Other

Identifiers

NCT01853150
2013-022

Details and patient eligibility

About

Freezing of gait (FOG) means that patients cannot walk without any known causes, other than parkinsonism, which is very disabling symptom. Patients descirbe their feeling of the feet suddenly being glued to the floor. Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain. Transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to the therapeutic effect of rTMS for the FOG.

Enrollment

12 patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Parkinson's disease or Primary progressive freezing of gait
  • age 18 and older
  • Freezing of gait

Exclusion criteria

  • pregnant or any, other medical, surgical, neurological or psychiatric conditions
  • other restrictions which prevent you from undergoing TMS recording, such as; surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), and/ or heart/cardiac lines
  • any past or current history of seizure disorder or epilepsy
  • unable to give informed consent

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

12 participants in 2 patient groups

rTMS Motor cortex
Experimental group
Description:
rTMS will be applied over the motor cortex
Treatment:
Device: rTMS Motor cortex
rTMS Supplementary motor area
Active Comparator group
Description:
rTMS will be applied over the supplementary motor area
Treatment:
Device: rTMS Supplementary motor area

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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