Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Treatment for Resistant Obsessive-compulsive Symptoms in Patients With Schizophrenia

Hospital de Clinicas de Porto Alegre

Status: Completed

Conditions: Schizophrenia; Obsessive-Compulsive Symptoms

Treatments: Device: SHAM rTMS; Device: Active rTMS

Study type: Interventional

Funder types: Other

Identifiers

NCT02105064

10-0426

Details and patient eligibility

About

This is a study to evaluate the efficacy of rTMS for relief of obsessive-compulsive symptoms in patients with schizophrenia.

Enrollment: 12 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of Schizophrenia (DSM-IV-TR)
• YBOCS ≥ 16

Exclusion criteria

• Mental Retardation
• Substance abuse
• Any contraindication to rTMS

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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12 participants in 2 patient groups

Active rTMS

Active Comparator group

Description:

rTMS over Supplementary Motor Area, 1hz, no pauses, 20 minutes per sessions. Total: 20 sessions.

Treatment:

Device: Active rTMS

Sham

Sham Comparator group

Description:

Sham stimulation, 20 minutes per session, total 20 sessions

Treatment:

Device: SHAM rTMS