Repetitive Transcranial Magnetic Stimulation (rTMS) in The Treatment of Gambling Disorder in Indonesia

University of Indonesia (UI)

Status: Not yet enrolling

Conditions: Gambling Disorder

Treatments: Device: Repetitive Transcranial Magnetic Stimulation (rTMS)

Study type: Interventional

Funder types: Other

Identifiers

NCT06182137

KET-1499-2023

Details and patient eligibility

About

Research has shown that cognitive-behavioral therapy (CBT) is an effective treatment for gambling disorder. Several studies had also been done to evaluate the effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) in addiction management, particularly in alleviating craving. A randomised controlled trial (RCT) of 30 subjects would be conducted to evaluate the effectiveness of transmodalistic therapy with a combination of rTMS and CBT for online gambling disorder.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 59 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects with pathological gambling (SOGS score ≥ 5)
• Subjects aged 18-59 years old
• Subjects who understand Bahasa Indonesia
• Subjects who agree to participate and receive treatment

Exclusion criteria

• Subjects with history of psychotic disorder, personality disorder, or sleep disorder according to ICD-11
• Subjects with history of neurostimulation
• Subjects with history of medical implant
• Subjects with history of severe neurological disorder, which causes seizure or loss of consciousness
• Subjects with intellectual disability
• Subjects with endocrinological disorders
• Subjects with contraindication during prior MR or other related procedures
• Subjects who are currently or expecting pregnancy
• Subjects with history of substance use in the last 6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

30 participants in 2 patient groups

rTMS and CBT

Experimental group

Description:

During 5 weeks of therapy, the subjects will undergo 12 CBT sessions combined with 15 rTMS procedures lasting about 30-60 minutes.

Treatment:

Device: Repetitive Transcranial Magnetic Stimulation (rTMS)

Sham and CBT

Sham Comparator group

Description:

During 5 weeks of therapy, the subjects will undergo 12 CBT sessions combined with 15 rTMS procedures (coil replaced with sham) lasting about 30-60 minutes.

Treatment:

Device: Repetitive Transcranial Magnetic Stimulation (rTMS)