Reproductibility of Lumbar Spine ADC Based on Different Post-processing Softwares

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Low Back Pain

Treatments: Other: Calculate the ADC scores

Study type: Observational

Funder types: Other

Identifiers

NCT02738424

IRBN642015/CHUSTE

Details and patient eligibility

About

Lumbar spine bone marrow is well explored in Magnetic Resonance Imaging (MRI) but some bone marrow diseases are hard to analyze with this method. Furthermore, there is heterogeneity in normal bone marrow, called apparent diffusion coefficient (ADC). Histological and technical factors appear to be the cause, but the possible influence of the employed post-processing software has never yet been evaluated. The purpose of this study is to determine if there is variability in lumbar bone ADC related to the post-processing software.

Full description

Lumbar spine bone marrow is well explored in MRI. Some bone marrow diseases are hard to analyze in conventional MRI, and diffusion-weighted imaging (DWI) could be an additional diagnostic feature. However, according to the literature, there is heterogeneity in normal bone marrow of the quantitative parameter that it provides, called apparent diffusion coefficient (ADC). Histological and technical factors appear to be the cause, but the possible influence of the employed post-processing software has never yet been evaluated. The purpose of this study is to determine if there is variability in lumbar bone ADC related to the post-processing software.

Enrollment: 98 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients undergoing lumbar spine MRI at University Hospital of Saint-Etienne

Exclusion criteria

• <18 years old

Trial design

98 participants in 2 patient groups

3T patients : Calculate the ADC scores

Description:

In this group all the patients perform a 3 Tesla RMI. With these data, three methods will be used to calculate the ADC score : Siemens, PACS (picture archiving and communication system) Carestream, Osirix. The ADC scores obtained with these three post-processing softwares will be compared.

Treatment:

Other: Calculate the ADC scores

1.5T patients : Calculate the ADC scores

Description:

In this group all the patients perform a 1,5 Tesla RMI. With these data, three methods will be used to calculate the ADC score : Siemens, PACS Carestream, Osirix. The ADC scores obtained with these three post-processing softwares will be compared.

Treatment:

Other: Calculate the ADC scores