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Rescue Carotid Stenting in Tandem Occlusions: 4-year Experience From a Comprehensive Stroke Centre

C

Can Tho Stroke International Services Hospital

Status

Completed

Conditions

Ischemic Stroke, Acute
Acute Stroke

Treatments

Procedure: Rescue carotid stenting

Study type

Interventional

Funder types

Other

Identifiers

NCT06397638
Rescue carotid stenting

Details and patient eligibility

About

The rescue carotid stenting has recently been an additional treatment followed by mechanical thrombectomy in tandem occlusions of the anterior circulation. Nevertheless, there were few data to date that support this beneficial treatment in Asia. The investigators hypothesized that this treatment related to improvement of clinical outcomes after procedure.

Full description

The anterior circulation made commonly up 70-80% of all ischemic strokes. The mechanical thrombectomy is the gold treatment standard in acute ischemic stroke due to large vessel occlusion of anterior circulation. Tandem occlusions are one of the acute lesions relating to the high poor clinical outcome rate. Besides, tandem characteristic is a challenge to perform endovascular therapy and save procedural time in the restoration blood flow to the cerebral artery territory infarction. Many studies demonstrated the roles of rescue carotid stenting with either proximal-to-distal or distal-to-proximal approach in the successful recanalization of tandem occlusions. However, few studies analyzed in detail this beneficial treatment in Asia. Therefore, the investigators conducted this study to assess whether rescue carotid stenting in the tandem occlusions to improve clinical outcomes at 3 months.

Enrollment

90 patients

Sex

All

Ages

19 to 100 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age > 18 years old
  • Onset to treatment time < 24 hours
  • NIHSS > 5
  • DWI-ASPECTS ≥ 5

Exclusion criteria

  • Premorbid mRS > 2
  • Loss to follow-up after discharge

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

90 participants in 1 patient group

Rescue carotid stenting
Experimental group
Description:
Rescue carotid stenting in tandem occlusions
Treatment:
Procedure: Rescue carotid stenting

Trial contacts and locations

1

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Central trial contact

Cuong C Tran, PhD

Data sourced from clinicaltrials.gov

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