Rescue Extracranial Vertebral Stenting in Tandem Occlusions (REVET)

Dr. Cuong Tran Chi

Status: Completed

Conditions: Vertebro Basilar Ischemia; Ischemic Stroke, Acute; Acute Stroke

Treatments: Procedure: Rescue extracranial stenting

Study type: Interventional

Funder types: Other

Identifiers

NCT06365294

REVET Study

Details and patient eligibility

About

The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. The investigators reported whether the additional rescue extracranial stenting improved clinical outcome by modified Rankin Scale (mRS) score within 3 months after the procedure

Full description

Acute vertebrobasilar artery occlusion is one of the cerebrovascular diseases with high disability and mortality rates. Although mechanical thrombectomy has recently been demonstrated an effective treatment for large vessel occlusions of posterior circulation, the treatment strategies depending on the specific pathophysiology. Tandem occlusion in posterior circulation is less frequently than in anterior one, comprises severe stenosis or occlusion of the extracranial vertebral artery ipsilateral to its intracranial and basilar occlusion. The recent studies showed the benefit of the "distal-to-proximal" approach, there were many tecniques to achieved the successful recanalization. Besides, the use of Dotter technique allowed 8F guiding catheter to cross the extracranial lesions easily and save the procedural time. However, the Diagnosis 5F-Dotter, like the Dilator-Dotter, has not been mentioned in previous studies. Therefore, the aim of the our study was to assess the improvement of outcomes at 3 months posttreatment in patients receiving rescue extracranial vertebral stenting

Enrollment: 9 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 18 years old
• Onset to treatment time < 24 hours
• NIHSS > 5
• pc-ASPECTS ≥ 5

Exclusion criteria

• Premorbid mRS > 2
• Extensive, bilateral brain-stem infarction on neuroimaging
• Cerebellar mass effect on neuroimaging
• Loss to follow-up

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

9 participants in 1 patient group

Rescue extracranial vertebral stenting

Experimental group

Description:

Rescue extracranial vertebral stenting in tandem occlusions

Treatment:

Procedure: Rescue extracranial stenting