RESCUE PROTOCOL AND FRESH EMBRYO TRANSFER

Istituto Clinico Humanitas

Status: Completed

Conditions: GnRH Trigger and Rescue Protocol

Treatments: Drug: GnRH agonist

Study type: Observational

Funder types: Other

Identifiers

NCT03837223

trigger

Details and patient eligibility

About

Ovarian Hyperstimulation Syndrome (OHSS) is one of the most dangerous complications of Assisted Reproductive Technologies (ART) cycles. The use in clinical practice of the GnRH antagonist has made it possible to perform the trigger with GnRH analogues reducing the risk of OHSS. The trigger with analogue increases the Abortion Rate (AR) and reduces the Ongoing Pregnancy Rate (OPR), because the luteal phase in these cycles is particularly deficient. To reduce this occurrence several studies have focused on the importance of support of the luteal phase. The aims of study is to evaluate OPR and AR in patients at intermediate risk of OHSS (<18 recovered oocytes) which performed GnRH trigger and rescue protocol.

Enrollment: 271 patients

Sex: Female

Ages: 18 to 38 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

AMH ( antimullerian hormone) > 3.5 ng / ml, AFC (antral follicles count) > 15 follicles and if more than 18 follicles with diam. 12mm to induction

Exclusion criteria

high risk of OHSS ( ovarian hyperstimulation syndrome)

Trial design

271 participants in 1 patient group

patients underwent "rescue protocols" and fresh embryotransfer

Description:

they were patients with good prognosis with a mean age of 34.13 ± 4.42 years, with a good ovarian reserve

Treatment:

Drug: GnRH agonist