Research and System Development on Functional 3D Optical Tomography for Skin Cell Imaging

National Taiwan University

Status: Unknown

Conditions: Optical Coherence Tomography; Skin Cell Imaging

Study type: Observational

Funder types: Other

Identifiers

NCT01557205

201202019RIC

Details and patient eligibility

About

The investigators will obtain human skin specimen (sized approximately 1 cm x 1 cm) for dermatological surgical patients in National Taiwan University Hospital, after informed consent was obtained. Human skin keratinocytes, fibroblasts, and melanocytes will be cultured from the human skin specimen. The three dimensional images of these cultured cells will be observed by a ultra-high resolution 3-dimensional optical coherence tomography.

Full description

The investigators will obtain human skin specimen (sized approximately 1 cm x 1 cm) for dermatological surgical patients in National Taiwan University Hospital, after informed consent was obtained. Human skin keratinocytes, fibroblasts, and melanocytes will be cultured from the human skin specimen. The three dimensional images of these cultured cells will be observed by a ultra-high resolution 3-dimensional optical coherence tomography.

Enrollment: 30 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged between 20 to 100.
• People who received benign skin tumor removal in dermatological surgical unit. OR
• People who received skin grafts (full thickness or split thickness) for reconstruction of surgical wounds after removing malignant skin cancer.

Exclusion criteria

• Age less than 20 years old,
• Psychiatric patients,
• Pregnant women.