Research Framework Exploring Sleep Health (REFRESH)

Scripps Translational Science Institute

Status: Enrolling

Conditions: Obesity; Mood; Sleep Apnea; Sleep

Study type: Observational

Funder types: Other

Identifiers

NCT05197738

IRB-21-7863

Details and patient eligibility

About

This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers. We are also collecting survey/questionnaire data on baseline health and sleep characteristics as well as bi-weekly assessments of sleep quality and mood. Overall, we aim to examine how sleep relates to physical and mental health in a large population of activity tracker users.

Enrollment: 100,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Residing within the United States
• Ability to use the REFRESH app on the participant's own smartphone device

Exclusion criteria

• In-ability to consent

Trial design

100,000 participants in 11 patient groups

High risk OSA

Description:

Cohort of individuals found to sleep have scores categorized as "High risk," on the Berlin questionnaire.

Low risk OSA

Description:

Cohort of individuals found to sleep have scores categorized as "Low risk," on the Berlin questionnaire.

Short sleepers

Description:

Cohort of individuals found to have average sleep duration of \< 7 hours per night. Individuals who sleep on average less than 6 hours per night will further be sub-categorized as very short sleeprs.

Long sleepers

Description:

Cohort of individuals found to have average sleep duration of \>9 hours per night.

Average lengths leepers

Description:

Cohort of individuals found to have an average sleep duration between 7 and 9 hours per night

Regular sleepers

Description:

Cohort of individuals whose standard deviation of sleep duration falls within 1 standard deviation of their mean sleep duration.

Irregular sleepers

Description:

Cohort of individuals whose standard deviation of sleep duration falls greater than 1 standard deviation of their mean sleep duration

Severe insomnia risk

Description:

Cohort of individuals whose scores on the Insomnia Severity Index would be categorized as severe

Moderate insomnia risk

Description:

Cohort of individuals whose scores on the Insomnia Severity Index would be categorized as moderate

No insomnia risk

Description:

Cohort of individuals whose scores on the Insomnia Severity Index would be categorized as low

Increased social jet lag

Description:

Individuals who are more than 1 hour less or more of sleep on weekdays compared to average weekend sleep.