Research in Autism: Parent Intervention

University of California San Diego

Status: Completed

Conditions: Autistic Disorder

Treatments: Behavioral: Picture Exchange Communication System; Behavioral: Pivotal Response Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01258465

MH39434

Details and patient eligibility

About

The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model. In one condition, randomly assigned children were provided with an intervention that typically results in acquisition of expressive words in a large percentage of children diagnosed as having autism, using a well-documented manualized intervention focused on verbal expressive communication only (Pivotal Response Training, PRT). In the other condi¬tion, randomly assigned children received a widely used intervention on the same social communication functions using a well-documented manualized augmentative system of intervention (Picture Exchange Communica¬tion System, PECS) that has been reported to produce verbal and nonverbal communication in large percentages of children diagnosed with autism. Children in the two conditions were compared for development of verbal and nonverbal communication, changes in disruptive behavior, changes in symptoms of autism, and general adaptive behavior gains. In addition, parent satisfaction and stress measures were gathered in order to assess the effects of each intervention on family functioning.

Enrollment: 39 patients

Sex: All

Ages: 24 to 47 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of Autistic Disorder or At Risk of Autistic Disorder
• Age 2-0 to 3-11 years of age
• Use of fewer than 10 functional words at intake

Exclusion criteria

• Primary diagnosis of mental retardation
• Neurologic pathology (e.g., PKU, encephalitis, brain trauma)
• Major sensory impairment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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39 participants in 2 patient groups

Pivotal Response Training

Active Comparator group

Description:

A naturalistic behavioral intervention designed to facilitate verbal communication.

Treatment:

Behavioral: Picture Exchange Communication System

Behavioral: Pivotal Response Training

Picture Exchange Communication System

Active Comparator group

Description:

Pictorially-based behavioral protocol designed to facilitate communication via picture icons.

Treatment:

Behavioral: Picture Exchange Communication System