Research of Revascularization in Immature Teeth With Periapical Periodontitis

Junqi Ling

Status: Unknown

Conditions: Periapical Periodontitis

Treatments: Procedure: apexification; Procedure: revascularization

Study type: Interventional

Funder types: Other

Identifiers

NCT01799187

jqling (Registry Identifier)

5010YT

Details and patient eligibility

About

Revascularization is an alternative new treatment of immature permanent teeth with necrotic pulp nowadays while apexification is the traditional therapy. The investigators suppose that revascularization is superior to apexification at developing the root of immature permanent teeth and reducing the risk of root fracture,and the research is designed.

Full description

The investigators design to collect a group of patients presenting immature permanent teeth with periapical periodontitis in certain criterion. The investigators will divide the patients into two groups randomly. One group will get treated with revascularization while the other with apexification. The investigators want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of revascularization.

Enrollment: 190 estimated patients

Sex: All

Ages: 6 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• clinical diagnosis of periapical periodontitis
• must be immature permanent teeth
• must be local Guangzhou

Exclusion criteria

• blood disease
• residual root that is advised to extract
• serious periodontitis
• women in pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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190 participants in 2 patient groups

revascularization

Experimental group

Description:

revascularization is is an alternative new treatment of immature permanent teeth with necrotic pulp. The use of triple antibiotic paste is followed by Induction of bleeding from the apical root during this intervention.

Treatment:

Procedure: revascularization

apexification

Active Comparator group

Description:

apexification is a traditional therapy of immature permanent teeth with necrotic pulp.calcium hydroxide is served as medication to induce the developing of root .

Treatment:

Procedure: apexification