Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases

Karadeniz Technical University

Status: Completed

Conditions: Abortion, Missed

Treatments: Diagnostic Test: study

Study type: Observational

Funder types: Other

Identifiers

NCT03767179

KTU

Details and patient eligibility

About

Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion

Full description

The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.

Enrollment: 60 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease

Exclusion criteria

• Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)
• Smoking
• Rejection to participate in the study.

Trial design

60 participants in 2 patient groups

Study Group

Description:

The study group consisted of 30 fertile, under 35 years old women who were included in the study for the first time missed abortus diagnosis.

Treatment:

Diagnostic Test: study

Control Group

Description:

30 cases with the same trimester, fertile, and under 35 years old who were referred to Obstetrics clinic, who had no systemic disease, were included in the study.

Treatment:

Diagnostic Test: study