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Research on the Effect and Mechanism of Aerobic Exercise on PD

J

Jilin University

Status

Unknown

Conditions

Parkinson's Disease
Physical Exercise

Treatments

Behavioral: aerobic exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT04651140
Zhang Ying

Details and patient eligibility

About

This trial is expected to recruit patients with primary Parkinson's disease and give them four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism

Full description

This trial is expected to recruit patients with primary Parkinson's disease who are distributed into tremor group and stiff group and give them the same kind of four consecutive weeks of aerobic exercise to observe its effect on Parkinson's disease and explore its mechanism

Enrollment

30 estimated patients

Sex

All

Ages

55 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Participants were diagnosed primary PD according to the 2015 MDS diagnostic criteria
  • Participants are between 55 and 65 years old

Exclusion criteria

  • Severe heart
  • liver dysfunction
  • kidney dysfunction
  • severe cognitive dysfunction
  • severe anxiety and depression
  • history of mental illness
  • history of cerebral infarction or ischemic attack in the past three months
  • acute myocardial infarction or acute coronary in the past three months
  • Parkinson's Pulse syndrome
  • medication history (drugs that improve blood circulation in the brain and increase the excitability of the nervous system)

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

30 participants in 2 patient groups

Tremor group
Active Comparator group
Description:
Participants in the tremor group have tremor as the main clinical manifestation
Treatment:
Behavioral: aerobic exercise
Stiff group
Active Comparator group
Description:
Participants in the tremor group have stiff as the main clinical manifestation
Treatment:
Behavioral: aerobic exercise

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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