Research on the Role of SLC1A5 in the Development of Esophageal Cancer

Fourth Affiliated Hospital of Guangxi Medical University

Status: Unknown

Conditions: Amino Acid Transport Disorder; Esophageal Cancer

Treatments: Other: SLC1A5 expression

Study type: Observational

Funder types: Other

Identifiers

NCT02633436

PJK201518

Details and patient eligibility

About

To explore the significance of Solute Carrier Family 1 Member 5 (SLC1A5) in the occurrence of esophageal cancer, by comparing the expression of SLC1A5 between esophageal cancer tissues and adjacent tissues.

Full description

This will be an observational study. The investigators will aim to enroll 100 male and female adult patients (aged 18 years and over) of all ethnicities/races, who have been referred to the Fourth Affiliated Hospital of Guangxi Medical University for esophageal cancer.

The investigators will be using a standardized data collection form. This is an observational study in which standard of care will be practiced and the patients are not placed at additional risk from participating in this study. However, as the investigators are collecting data prospectively, all participants will sign consent. An attempt will be made to see if there is a correlation between the expression of SLC1A5 with esophageal cancer.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with histologically proven esophageal cancer;
2. Age ≥18 years;
3. All patients must sign consent forms voluntarily;

Exclusion criteria

1. Inability to obtain histologic proof of malignancy.
2. Age <18 years;

Trial design

100 participants in 2 patient groups

cancer tissues

Description:

SLC1A5 expression of esophageal cancer tissues from patients

Treatment:

Other: SLC1A5 expression

paired adjacent tissues

Description:

SLC1A5 expression of paired adjacent esophageal tissues from patients

Treatment:

Other: SLC1A5 expression