Resect and Discard Strategy in Clinical Practice

Valduce Hospital

Status: Completed

Conditions: Endoscopic Assessment; Colonic Polyps; Endoscopic Surveillance; NBI

Treatments: Other: endoscopic assessment of colonic polyps

Study type: Observational

Funder types: Other

Identifiers

NCT01462123

RD 2010

Details and patient eligibility

About

Nowadays, post-polypectomy surveillance intervals are determined by combining endoscopic and pathologic data. Real-time imaging technologies, have shown promising results in discriminating adenomatous from non-adenomatous polyps.

The "resect and discard strategy" for small polyps (based on real-time assessment of the histology and on the endoscopic resection without pathological examination) has been shown to be cost-effective in simulation models. No data exist about the impact of this strategy in clinical practice.

The aim of present study was to assess whether the systematic use, in the everyday clinical practice, of the "resect and discard strategy" allows to correctly manage patients with small colonic polyps.

Enrollment: 286 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• consecutive adult outpatients undergoing colonoscopy for routine clinical indications

Exclusion criteria

• surveillance interval was not necessarily directed by endoscopic findings (history of colorectal cancer, inflammatory bowel disease, hereditary polyposis syndromes, hereditary non-polyposis colorectal cancer)
• colonoscopy was performed without NBI technology
• at least one lesion > 10 mm or < 10 mm but with morphologic features suspect for malignancy (depressed or ulcerated lesions) was detected
• bowel preparation was inadequate
• caecal intubation was not accomplished
• polyps could not be resected for concomitant anticoagulation treatment, 7) polyps were resected but not retrieved for pathology.

Trial design

286 participants in 1 patient group

small polyps patients

Description:

Patients with one small polyps at colonoscopy

Treatment:

Other: endoscopic assessment of colonic polyps