Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation

Shanghai Minimally Invasive Surgery Center

Status: Not yet enrolling

Conditions: Slow Transit; Constipation

Treatments: Procedure: Laparoscopic total colectomy + low resection of rectum; Procedure: Laparoscopic total colectomy + High resection of rectum

Study type: Interventional

Funder types: Other

Identifiers

NCT04525248

MISC-Constipation-Rectum

Details and patient eligibility

About

Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum

Full description

The investigators are going to study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum. High resection is defined as resection at 12~15cm from anus and low resection as 6~8cm.

Enrollment: 78 estimated patients

Sex: All

Ages: 15 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed as constipation according to Rome IV criteria
• Diagnosed as slow transit constipation
• With more than 2 years' drug treatment or with outlet obstruction or with surgical history

Exclusion criteria

• Colon cancer
• History of colon, rectum, anus surgery
• With severe cardio, renal, neural disease
• Pregnant patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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78 participants in 2 patient groups

High resection

Active Comparator group

Description:

Laparoscopic total colectomy + High resection of rectum

Treatment:

Procedure: Laparoscopic total colectomy + High resection of rectum

Low resection

Experimental group

Description:

Laparoscopic total colectomy + Low resection of rectum

Treatment:

Procedure: Laparoscopic total colectomy + low resection of rectum