ClinicalTrials.Veeva

Menu

Residual Neuromuscular Blockade in Pediatric Anesthesia (REPEB)

B

Brno University Hospital

Status

Completed

Conditions

Residual Neuromuscular Blockade

Treatments

Device: Residual neuromuscular blockade measurement

Study type

Observational

Funder types

Other

Identifiers

NCT02939911
KDAR FN Brno 2016/2

Details and patient eligibility

About

Residual neuromuscular blockade (RNB) is frequent and it is associated with postoperative morbidity and mortality. The incidence of the RNB in pediatric anesthesia is currently not known. The aim of this prospective observational cohort study is to evaluate the early RNB just before extubation and late RNB at the time of arrival to postanesthetic care unit (PACU).

Full description

Residual neuromuscular blockade (RNB) is frequent and it is associated with negative impact on postoperative morbidity and mortality. The incidence of the RNB in adult is well described, however in pediatric subpopulation it is currently not known. The aim of this prospective observational cohort study is to evaluate the early RNB just before extubation and late RNB at the time of arrival to postanesthetic care unit (PACU). In the trial will be enrolled all pediatric patients (28 weeks of age and older - 19 years old) whom will be administered neuromuscular blocking agent during anesthesia. The demographic data will be collected including: age, weight, type of surgery, ASA status. The anesthesia management will be described including: airway management, type and cumulative dose of neuromuscular blocking agent (NMBA) and time and dose of the last administered bolus of NMBA. The residual neuromuscular blockade will be measured according to the standards: TOF Watch accelerometry at the moment prior to extubation (two measurements) in TOF mode and at the arrival to postanesthetic care unit (PACU) (two measurements) in TOF mode.

Enrollment

291 patients

Sex

All

Ages

29 weeks to 19 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Paediatric patients undergoing surgery with neuromuscular blocking agents were administered with the age limits

Exclusion criteria

  • weight under 3000 grams
  • neuromuscular disease
  • haemodynamic impairment (vasopressor need)
  • planned postoperative mechanical ventilation

Trial design

291 participants in 1 patient group

Paediatric patients after NMBA administration
Description:
Paediatric patients undergoing surgery with neuromuscular blockade
Treatment:
Device: Residual neuromuscular blockade measurement

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems