Resilient Together for Dementia (RT-D ADRD)

Mount Sinai Health System

Status: Completed

Conditions: Alzheimer's Disease and Related Dementias

Treatments: Behavioral: Resilient Together for Dementia

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06421545

1K23AG075188-01A1 (U.S. NIH Grant/Contract)

GCO 23-0519

Details and patient eligibility

About

The proposed study will establish the feasibility, acceptability and credibility of a novel live video dyadic resiliency intervention, Resilient Together for Dementia (RT-D), aimed at preventing chronic emotional distress and preserving quality of life among dyads at risk for chronic emotional distress early after a diagnosis of Alzheimer's disease or a related dementia (ADRD).

Full description

Both persons living with dementia (PWDs) and their spousal care-partners experience high levels of clinically elevated emotional distress, which can become chronic without treatment and negatively impact the health, quality of life, communication, and care-planning of both partners. A tailored dyadic intervention, such as the proposed Resilient Together for Dementia, delivered over live video to this at risk population during the window of opportunity when PWDs can participate has the potential to prevent chronic emotional distress and preserve quality of life for PWDs and their loved ones.

Enrollment: 12 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

PWD inclusion criteria are:

• Recent (~1 month) chart documented ADRD diagnosis,
• ADRD symptom onset after age 65 ,
• cognitive assessment scores and symptoms consistent with early stage dementia, as determined by the Clinical Dementia Rating Scale scores of .5 or 1.0
• cognitive awareness of his/her problems (as determined by the treating neurologist), and
• ability to understand study and research protocol, as determined by a standardized teach-back method assessment84.

Additional inclusion criteria for dyads are:

• English speaking adults (18 years or older),
• dyad lives together,
• at least one partner endorses clinically significant emotional distress during screening (>7 on Hospital Anxiety and Depression scale subscales)

Exclusion Criteria:

• patient is deemed inappropriate by the neurology team,
• either partner has a co-occurring terminal illness,
• patient was diagnosed with forms of dementia with clinical profiles that would preclude participation (e.g., Frontotemporal Dementia- behavioral variant), as determined by treatment team.

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

Open Pilot RT-D Dyads

Experimental group

Description:

Persons living with dementia (PWDs) and their spousal care-partners

Treatment:

Behavioral: Resilient Together for Dementia