Resistance Exercise and Cognition in People With Type 1 Diabetes

Dasman Diabetes Institute

Status: Enrolling

Conditions: type1diabetes

Treatments: Behavioral: Morning Exercise; Behavioral: Afternoon Exercise; Behavioral: Habitual Physical Activity

Study type: Interventional

Funder types: Other

Identifiers

NCT05963152

RA HM-2023-010

Details and patient eligibility

About

The aim of the current study is to determine the effects of resistance exercise on performance of the Paced Auditory Serial Addition Test and the Colour Trails Test.

Enrollment: 54 estimated patients

Sex: All

Ages: 21 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Physician confirmed type 1 diabetes for at least 1 year
• Stable insulin therapy for 3 months prior to the study

Exclusion criteria

• BMI of 45 or higher
• BP of 160/100mmHg or higher
• autonomic neuropathy
• severe proliferative retinopathy
• joint or limb injuries preventing weight-bearing activity
• autonomic neuropathy
• severe proliferative retinopathy
• any other medical condition that prevents participants from exercising safely.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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54 participants in 3 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

Habitual Physical Activity

Treatment:

Behavioral: Habitual Physical Activity

Morning exercise

Experimental group

Description:

Exercise training between 6-10am

Treatment:

Behavioral: Morning Exercise

Afternoon exercise

Experimental group

Description:

Exercise training between 4-8pm

Treatment:

Behavioral: Afternoon Exercise