Resistance Exercise in Severe Knee Osteoarthritis (RTOA)

University of Valencia

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Other: Resistance Exercise; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06664905

OA-2023

Details and patient eligibility

About

This study aim to evaluate pain after different resistance training protocols (placebo, 4 sets of 10RM, 8 sets of 10 RM and 12 sets of 10RM) in patients with severe knee osteoarthritis.

Enrollment: 28 patients

Sex: All

Ages: 55 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• men and women at least 55 years old
• diagnosed with severe knee OA
• scheduled for unilateral Total Knee Arthroplasty (TKA) surgery

Exclusion criteria

• pain in the contralateral (non-studied) limb (maximum ≥80 of 100 mm on a visual analog scale (VAS) during daily activities)
• another hip or knee joint replacement in the previous year
• any medical condition in which exercise was contraindicated
• participated in exercise programs (>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study
• history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of study tasks

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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28 participants in 4 patient groups

Placebo

Active Comparator group

Description:

control, with no exercise

Treatment:

Other: Placebo

4 sets

Experimental group

Description:

4 sets of 10RM of knee extensions

Treatment:

Other: Resistance Exercise

8 sets

Experimental group

Description:

8 sets of 10RM of knee extensions

Treatment:

Other: Resistance Exercise

12 sets

Experimental group

Description:

12 sets of 10RM of knee extensions

Treatment:

Other: Resistance Exercise