Resistance Training and Sex Hormone Concentrations During the Menstrual Cycle

Southern Illinois University Edwardsville

Status: Unknown

Conditions: Women's Health

Treatments: Behavioral: Resistance Training

Study type: Interventional

Funder types: Other

Identifiers

NCT04163380

111B

Details and patient eligibility

About

Although there are numerous studies showing effects of aerobic training on sex hormone concentrations, research analyzing the fluctuation of sex hormones in response to resistance training (RT) is lacking. The objective of this project is to analyze estradiol (E2) and progesterone (P4) responses to an acute resistance training session throughout different phases of the menstrual cycle. This proposed research has strong implications for exercise prescription and for women in general, but more importantly will allow exercise physiologists, coaches, personal trainers, or nutritionists optimize exercise programming around women's menstrual cycle.

Enrollment: 25 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Eumenorrheic females
• Age 18-45 years old
• BMI of 18.5-34.99 kg/m2

Exclusion criteria

• Practice exercise more than 2 days/week in the last 3 months.
• Cardiovascular, metabolic, pulmonary or muscular-skeletal condition
• Taking medications that affect metabolism (e.g. oral contraceptives)
• Irregular menstrual cycles

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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25 participants in 4 patient groups

Early Follicular Phase (EFP)

Experimental group

Treatment:

Behavioral: Resistance Training

Late Follicular Phase (LFP)

Experimental group

Treatment:

Behavioral: Resistance Training

Early Luteal Phase (ELP)

Experimental group

Treatment:

Behavioral: Resistance Training

Late Luteal Phase (LLP)

Experimental group

Treatment:

Behavioral: Resistance Training