Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes

University of Missouri (MU)

Status

Completed

Conditions

Exercise Intervention

Treatments

Behavioral: Resistance training

Other: Conventional physical activity guidelines

Study type

Interventional

Funder types

Other

Identifiers

NCT04906525

2054484

Details and patient eligibility

About

The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Full description

The overall objective of this study is to investigate the effects of resistance training on the gut microbiome and cardiometabolic outcomes in adults with overweight and obesity.

Enrollment

34 patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age 18-35 years
BMI: 25-45 kg/m2
Sedentary lifestyle
Consistent diet patterns
Weight-stable (<4 kg change over the last 3 mo)
Willingness to adhere to resistance training protocol and not change diet
Non-smoker >1 year or more

Exclusion criteria

Disabilities preventing adherence to resistance training protocol
Recent start of medications that affect metabolism or appetite
Antibiotics
Diabetes
Drug therapy for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia
Uncontrolled hypertension and blood pressure ≥ 180/110
Gastrointestinal disease and/or bariatric surgery
Smoking
Illicit drug use
Pregnant or lactating individuals