Resistance Training in Knee Osteoarthritis

Federal University of São Paulo

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Knee Osteoarthritis

Treatments: Other: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01099371

FDAAAA

Details and patient eligibility

About

The purpose of this study is to determine whether:

1. Progressive resistance training improves pain and disability
2. Progressive Resistance training improves muscular strength, ability to walk and quality of life

Full description

Patients in experimental group participated in a 12-week progressive resistance training using a repetition maximum (RM) exercise in which patients performed 1RM with the maximum bearable weight. Once the 1RM was determined, training was divided into the following regimen: 2 series of 8 repetitions, the first with 50% and the second with 70% of 1RM.

The exercises were knee extension and flexion and hip abduction and adduction, all performed in machines. The 1RM load was reevaluated every 2 weeks.

The control group remained on a three-month waiting list for physiotherapy. Patients were assessed for pain, function, quality of life, muscle strength and six-minute walk test.

Enrollment: 70 estimated patients

Sex: Female

Ages: 40 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Woman
• Age between 40-70 years old
• Pain between 3 and 8 on a 10-point numeric pain scale
• Radiographically confirmed knee OA

Exclusion criteria

• Inflammatory diseases or any comorbidity that prohibit exercises, regular physical activity
• Trip plans for the next 12 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 1 patient group

exercise

Experimental group

Treatment:

Other: exercise