Resistance Training in Patients With Chronic Obstructive Lung Disease (COPD): Whole Body Vibration Versus Conventional Resistance Training (REWORK)

Ghent University Hospital (UZ)

Status and phase: Completed; Phase 3

Conditions: COPD

Treatments: Behavioral: Conventional resistance training program; Behavioral: Whole body vibration resistance training program

Study type: Interventional

Funder types: Other

Identifiers

NCT01135966

2010/157

Details and patient eligibility

About

Pulmonary rehabilitation has been emerged as a recommended standard of care for patients with chronic lung disease based on a growing body of scientific evidence. A set of evidence-based guidelines were published in American College of Chest Physicians (ACCP) and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR). Since then, the published literature in pulmonary rehabilitation has increased substantially, and other societies have published important statements about pulmonary rehabilitation (eg, the American Thoracic Society and the European Respiratory Society).

In patients with COPD, there is a strong scientific basis for implementing conventional resistance training (CRT) in addition to endurance training. Endurance training, such as walking, is a key component of pulmonary rehabilitation and improves in exercise tolerance and muscular endurance. However, this type of training may not reverse muscle weakness or atrophy. For that reason, strength training seems to be the optimum training modality to increase muscle mass and strength.

Recently, Whole-Body-Vibration (WBV) training has been promoted as an alternative for resistance training on multigym equipment. In WBV training, the subject stands on a platform that generates vertical sinusoidal vibration, during which static and dynamic exercises can be performed.

The present study is conducted to provide an answer on the following question: will a resistance training program, such as the whole body vibration, be even effective than a conventional resistance training program in patients with COPD.

Enrollment: 62 patients

Sex: All

Ages: 40 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with COPD candidate for pulmonary rehabilitation
• Men and female between 40 and 80 years of age
• Written informed consent to participate

Exclusion criteria

• Severe cardiac, neurological and orthopedic co-morbidity interfering with exercise training.
• Pacemaker
• Hip, knee of shoulder prosthesis or recently introduced spirals, metal pens, bolts or plates
• Uncontrolled diabetes, epilepsy or migraine
• Osteoporotic or metastatic fractures, acute hernia, discopathy, spondylitis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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62 participants in 2 patient groups

Conventional training

Active Comparator group

Treatment:

Behavioral: Conventional resistance training program

Whole body vibration training

Experimental group

Treatment:

Behavioral: Whole body vibration resistance training program