Resistance Training in People Living With HIV/AIDS

State University of Maringá

Status: Completed

Conditions: HIV/AIDS

Treatments: Other: Exercise group

Study type: Interventional

Funder types: Other

Identifiers

NCT03879993

Exercise and HIV

Details and patient eligibility

About

The aim of this study will be to verify effects of resistance training in people living with HIV/AIDS.

Full description

The aim of this study was verify effects of resistance training in cognitive function, body composition and biochemical parameters of inflammation and oxidative stress in people living with HIV/AIDS. The sample was composed by patients with HIV/AIDS of both sexes. The patients were randomized in two groups, a exercise group (EG), which was receive intervention with eight weeks of resistance training, and a control group (CG), that was not to do exercise. The cognitive function was analyzed with Stroop Test and Trail Test; body composition was evaluated by bioimpedance; blood tests was use to analyze biochemical parameters of inflammation and oxidative stress. For statistical analysis was used ANOVA of two factors for repeated measurements, having the (EG and PG) group and the time (pre and post exercise). Level of significance adopted was P < 0,05.

Enrollment: 49 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnostic for HIV/AIDS.
• Clinical condition and viral count stabilized.
• Have been using (HAART) for 6 months or more.
• Not have participated in physical exercise programs in six months before beginning of study.
• Not have muscle or joint injuries that make it impossible to practice physical activity.
• Not be pregnant.

Exclusion criteria

• Not attending more than 15% of the intervention sessions or visits to the laboratory.
• Aggravation of the disease.
• Stick to a physical activity program in addition to that offered by the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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49 participants in 2 patient groups

Exercise group

Experimental group

Description:

Exercise group was resistance training three times per week, during 45 to 60 minutes per day. Training program was composed by bench press, leg press 45°, lat pulldown, knee extension, dumbbell lateral raise, horizontal leg curl, triceps pulldown, seated calf raise, biceps curls and abdominal. Participants should complete 3 series with 8-12 repetitions of each exercise, which was supervised by trained research personnel. There were 60 seconds of interval between series and exercises were separated by a 120 seconds recovery period.

Treatment:

Other: Exercise group

Control group

No Intervention group

Description:

Control group was not do any exercise during intervention period. Participants was asked to keep their habitual routine until finish the final evaluations.