Resistance Training on Growth Factors

Air Force Military Medical University of People's Liberation Army

Status: Not yet enrolling

Conditions: Cognitive Function

Treatments: Other: Low intensity resistance training; Other: High intensity resistance training

Study type: Interventional

Funder types: Other

Identifiers

NCT06114550

zuochongwen

Details and patient eligibility

About

The goal of this clinial trial study is to explore the effect of high or low intensity resistance training (LIRT) under similar training volume on change in serum levels of BDNF, IGF-1, VEGF, irisin, and plasma Hcy in young adults.The main questions it aims to answer are:

1. Whether high and low intensity will increase the serum levels of BDNF, IGF-1, VEGF, irisin, and reduce plasma Hcy.
2. whether a greater magnitude of change would be suffer in low intensity group when compared to high intensity group, as an effect of greater physiological adaptation produced by more repetitions required to complete.

Participants will performe two different intensity resistance training (HIRT, at 80%1RM with 12 repetitions and 4-5 sets and LIRT, at 40%1RM with 24 repetitions and 4-5 sets).

Researchers will compare the training effects of two different training on these growth factors.

Enrollment: 12 estimated patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 18 to 30 years
• no experiencing musculoskeletal disorders or sports injuries
• had not participated any regular aerobic endurance or resistance training with in the previous half years
• no smoking habit or intake alcohol and other medication (e.g., steroid hormone)
• good general body condition without any chronic diseases (e.g., osteoarthritis, metabolic syndrome or arthritis)

Exclusion criteria

• experiencing musculoskeletal disorders or sports injuries in recent 1 month
• had regular resistance training exercise
• intake any supplementary(drug and hormone)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

12 participants in 2 patient groups

High-intensity resistance training group (HIRT)

Experimental group

Description:

All subjects were instructed to conduct HIRT consisted of 4-5 sets of 12 repetitions at 80%1RM, with 1-2 minutes rests between each set.

Treatment:

Other: High intensity resistance training

low-intensity resistance training group (LIRT)

Experimental group

Description:

All subjects were instructed to conduct LIRT consisted of 4-5 sets of 24 repetitions at 40%1RM, with same period) in random order.

Treatment:

Other: Low intensity resistance training