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Resistant Arterial Hypertension Cohort Study (RAHyCo)

University Hospitals (UH) logo

University Hospitals (UH)

Status

Completed

Conditions

Hypertension
Resistant Hypertension
Essential Hypertension

Treatments

Drug: chlorthalidone
Behavioral: motivational intervention for non-compliant individuals
Drug: standardized anti-hypertensive treatment

Study type

Observational

Funder types

Other

Identifiers

NCT01083017
CER09-237 (Other Identifier)
33CM30-124087 (Other Grant/Funding Number)
RAHyCOstudy

Details and patient eligibility

About

The purpose of this study is to investigate the epidemiology of resistant hypertension, evaluate the efficacy and feasibility of a standardized drug treatment regimen (including the randomization of two doses of the diuretic used - chlorthalidone), study two interventions in the group of patients that is non-compliant, and study environmental and genetic variables of individuals with resistant hypertension in a family design.

Enrollment

74 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • informed consent
  • resistant hypertension at the moment of inclusion
  • 18 years or more, both sexes are included
  • women at reproductive age: consenting to use oral contraception

Exclusion criteria

  • patients mentally impaired or unable to give informed consent
  • patients speaking only a foreign language other than French, German, or English
  • patients living far away, making the study visits not practical

Trial design

74 participants in 3 patient groups

chlorthalidone
Treatment:
Drug: chlorthalidone
motivational invervention
Description:
motivational interview(s) vs. repeated calls vs. no particular intervention
Treatment:
Behavioral: motivational intervention for non-compliant individuals
standardized anti-hypertensive treatment
Treatment:
Drug: standardized anti-hypertensive treatment

Trial contacts and locations

3

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Data sourced from clinicaltrials.gov

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