Resistant Starch, Antioxidant Status and Insulin Resistance

Urmia University of Medical Sciences

Status: Completed

Conditions: Overweight; Obesity

Treatments: Dietary Supplement: Maltodextrin; Dietary Supplement: Hi-maize resistant starch

Study type: Interventional

Funder types: Other

Identifiers

NCT01992783

umsu.rec.1392.75

Details and patient eligibility

About

The aim of this study is to evaluate whether supplementation with resistant starch improves biomarkers associated with antioxidant status and insulin resistance in subjects with overweight and obesity.

Enrollment: 21 patients

Sex: All

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Overweight and obese adults
• Age: 20-50 years

Exclusion criteria

• weight loss or gain (more than10%) over the past 6 months, or weight loss (more than 5%) over the past 1 month
• pregnancy, lactation or menopause
• History of acute disease or clinical evidence of cancer, acute or chronic inflammatory diseases, cardiovascular disease, renal disease, liver disease, thyroid or endocrine disease
• Gastrointestinal disease of which ingredients found in the study products have adverse effects on that
• Use of antihypertensive, lipid lowering or glucose lowering medications
• Taking antioxidant, vitamin, and/or mineral supplements
• smoking

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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21 participants in 2 patient groups, including a placebo group

Hi-maize resistant starch

Experimental group

Description:

13.5 g/day

Treatment:

Dietary Supplement: Hi-maize resistant starch

Maltodextrin

Placebo Comparator group

Description:

13.5 g/day

Treatment:

Dietary Supplement: Maltodextrin