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Resistant Starch on Glucose and Insulin Sensitivity in Individuals With Type 2 Diabetes

K

Kansas State University

Status

Completed

Conditions

Hyperglycemia

Treatments

Dietary Supplement: Resistant Starch Type 4-Cooked
Dietary Supplement: Resistant Starch Type 4-Raw
Dietary Supplement: Shredded Wheat

Study type

Interventional

Funder types

Other
Industry

Identifiers

NCT00691249
KSU-HML-RSt3

Details and patient eligibility

About

This study will test the effects of resistant starch type 4 on blood sugar and hunger in adults with Type 2 diabetes.

Full description

To measure the blood glucose response, after an overnight fast, blood samples will be collected before eating and 15, 30, 45, 60, 90, and 120 minutes after eating each bar. The incremental area under the curve was used to calculate glycemic index. The investigators will also measure the second meal effect by measuring the metabolic response (glucose, insulin, and gut hormones) after a standardized lunch two hours following the first assessment.

Enrollment

10 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Type 2 Diabetics

Exclusion criteria

  • Diagnosed with other metabolic disorders
  • Allergies to wheat
  • Non-smokers

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

10 participants in 5 patient groups, including a placebo group

1
Experimental group
Description:
Resistant starch type 4-Raw
Treatment:
Dietary Supplement: Resistant Starch Type 4-Raw
Dietary Supplement: Resistant Starch Type 4-Raw
2
Experimental group
Description:
Resistant starch type 4-Raw
Treatment:
Dietary Supplement: Resistant Starch Type 4-Raw
Dietary Supplement: Resistant Starch Type 4-Raw
3
Experimental group
Description:
Resistant starch type 4-Cooked
Treatment:
Dietary Supplement: Resistant Starch Type 4-Cooked
Dietary Supplement: Resistant Starch Type 4-Cooked
4
Experimental group
Description:
Resistant starch type 4-Cooked
Treatment:
Dietary Supplement: Resistant Starch Type 4-Cooked
Dietary Supplement: Resistant Starch Type 4-Cooked
5
Placebo Comparator group
Description:
Shredded wheat
Treatment:
Dietary Supplement: Shredded Wheat

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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